痛入骨髓

Explanation: Pain to the bone. Analogy to the extreme hate or sadness. 　　Source: "Warring Yan policy three" going to Heaven and our admiration tears General Fan said 'I often pain in the bone marrow of each read, I do not know the total care of the ear! '" 　　Examples: Duke Hsiang of Sung Bo Chi desire, is a tease Chu, anti by the big shame, feelings of resentment, ~, but hate the force can not be reported. (Ming Feng Meng, "Eastern Zhou Zhi" Thirty-fourth back)