疚心疾首

Explanation: Regrets: chronic illness, anxiety. Because of guilt and feeling the pinch. Uneasy, headache, brain swelling. Very sad sadness or anxiety described. 　　Usage: Joint type; as predicate; containing derogatory 　　Source: Cui Tang E "in Temple Beth Ms. Zhu Zhi Fu Zhao together": "to heir ordered chicken Lin, Ran-year-old complex, remorse Xinji first, when the ceremony is also read, offerings of Youzhu." Thesaurus:  Sad day to call