痛心入骨

Explanation: Describe the sad to the extreme. 　　Usage: The main predicate; as predicate, attributive; describe the sad to the extreme 　　Source: Southern Song Fan Ye, "Han Yuan Tan Biography": "is iT people in, everyone grieved Such is Life, when people can not hurt relative tolerance also." 　　Examples: Each and Liuzuo general, Sungong You were on the matter, not a bad idea - compared to sadness. ("Three Kingdoms Shu Chi Chuan Sun dry") Thesaurus:  be transported with grief, in deep sorrow, Bitter, to hate to the marrow, Mandarin duck into the marrow, hate (one's) guts, chomp abhor, howl, Disease first frown, to hate evil as much as one hates an enemy., Blood through gum chewing, Chomp Heart rot, hurt (of hatred, etc.) strongly felt, Detest Pain disease, swear revenge and want to eat the flesh of the enemy and sleep on his skin, grief and indignation be filled in the chest, Jishoucuzi