Meningococcal (meningococcus) Meningococcal resistance to weak, to cold, sunlight, heat, dry, sensitive to both UV and general disinfectant. Of the sulfonamides, penicillin, chain toxins, are sensitive to chlortetracycline, but prone to drug resistance. According to meningococcal capsular polysaccharide antigens of different surface, the bacteria will be divided into a, b, c, d, x, y, 29e, and w135 nine serum group, belonging to the human disease multiple a, b, c group , more than 95% of cases as a group, some areas that b group and c groups. x, y, z, etc. are often found in the carriers very little disease. In accordance with outer membrane protein antigen (type specific) will be divided into several different serotypes of serogroups. The main pathogenic meningococcal substance capsule, pili, lipopolysaccharide. Meningococcal sojourn in normal nasopharyngeal cavity is usually in about 5 ~ 10% of the nasopharynx of healthy individuals with the pathogen, prevalence of up to 20 ~ 70%, but 90% are not disease carriers, a few rise to the nose pharyngitis, caused severe bacteremia, only 1 to 2% of the people, by the blood or lymph to reach the spinal cord caused by suppurative meningitis in film. Carriers and patients is the source of infection. Meningococcal infection through droplets, or through contact with respiratory secretions of patients infected with contaminated items. Incubation period of about 1 to 4 days. The occurrence of this disease and is closely related to immunity, when the body resistance is low, the invasion of nasopharyngeal bacteria multiply and invade the bloodstream, causing bacteremia and sepsis, the patient developed chills, fever, nausea, vomiting, hemorrhagic skin rash, skin rash can be found within the bacteria. Serious violations of cerebral spinal membrane, the occurrence of purulent meningitis, headache, vomiting injection, tenaciously till the neck meningeal irritation. Even as both sides of the adrenal hemorrhage, adrenal failure occurs, toxic shock. The production of the above symptoms, and bacterial autolysis and death related to the release of large amounts of endotoxin. Neisseria meningitidis and Neisseria gonorrhoeae can produce an extracellular enzyme that lga protease, that specifically cracking people lga1, thereby destroying the normal human immune function, its pathogenic role in more and more attention. Adult strong immunity against meningococcal infection after only 1 to 2% of the performance of meningitis. Children with weakened immune systems, the higher the incidence of infection. The mother to fetus through the placenta antibody, so infants less than 6 months rarely suffer from meningitis. Produced by the body after infection capsular polysaccharide antibodies, anti-outer membrane protein antibody, a specific anti-meningococcal role in anti-LPS antibodies may have some significance and toxicity. Of susceptible children injected with purified ECM group specific polysaccharide vaccine, the specific prevention. Sulfonamides can be taken orally during epidemic prevention. ECM preferred sulfonamide treatment, can also be used penicillin, chloramphenicol or ampicillin.
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Wikipedia Daquan
Meningococcal A meningitis epidemic caused by gram-negative purulent meningitis. Showed a kidney-shaped or bean-shaped, arranged in pairs, concave relative, sizes, no spores, no flagella, as a post of aerobes. Resistance is weak, on the dry, high temperature, low temperature, sulfa drugs and antibiotics Dengjun very sensitive.
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English Expression
n.: meningococcus, neisseria meningitidis
Containing Phrases
Meningococcus illness
meningococcemia
Meningitis ball bacterium catch
meningococcus carrier
Meningococcus character encephalitis
Meningococcus character carditis
cluster Meningococcus Glycan bacterin
Meningococcal Polysaccharide Vaccin
cluster Meningococcus Glycan bacterin
meningococcal meningitis
Ictus character Meningococcus meningoencephalitis
cluster Meningococcus Glycan bacterin injection
Meningitis ball bacterium catch After arthritis
Meningococcus character After the ball ophthalmoneuritis
Meningococcus character Adrenal syndrome
meningococcus Glycan bacterin
a short temper Meningitis ball bacteremia
Meningococcus character conjunctivitis
carditis
Meningococcus character pericarditis
Meningococcus character septicemia
Meningococcus character endocarditis
Chronicity meningitis ball bacteremia
Meningococcus character ophthalmoneuritis
Wofu Syndrome Meningococcus character
Meningococcus character Flow nature paranephritis
Meningococcus encephalitis Myelitis and encephalomyelitis