[中文名称] 堆心菊苦素
[英文名称] heleniamarin
[别名]
[化学名称] 2h-1,4-dioxabicyclopent [cd,f]azulene-3,9-dione-3,9-dione, 2a,4a,5,6,8,9a,9b,9c-octahydro-2-hydroxy-2,2a,6,9a-tetramethyl-, [2s-(2α,2aβ,4aα,6β,9aα,9bβ,9cβ)]-
[分 子 式] c17h22o5
[分 子 量] 306.14
[物理性质] 棱柱状结晶(乙醚), 熔点151～153°, (α)25d+58.5°(c=0.25, 氧仿) 。lrλkbrmax cm-1: 3450(br.), 1755(sh), 1750; uvλmeohmax nm(ε): 278(66),226(335); msm/e(％): 306, 283(3), 264(30), 246(3), 235(100); nmr(cdci3)δ: 1.22(s,3h), 1.23(d, j=7), 1.28(s,3h), 150(s,3h), 2.82(t,j=2,1h), 2.97(t,j=2,1h), 3.60(s,1h,与d2o可交换), 4.07(d,j=6.6,1h), 5.03(br,t,j=1,1h), 5.78(br.s,1h) 。
[成分分类]
[药理作用] 对人体鼻咽癌(kb)细胞有细胞毒活性
[毒性]
[不良反应]
[用途]
[成分来源] 菊科植物苦味堆心菊 helenium amarum (rafin.)h. rock. |
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