2, the of Gastrodia agent Armillaria fermentation liquid sodium pentobarbital night sleep time in the control group only to sodium pentobarbital, the righting reflex as an indicator of sleep. The results of the treatment group and control group significant difference.
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[] Http://www.apy.cc Leigongshan wild Gastrodia I. Product Overview Thunder Mountain Wild Gastrodia (Leigong Mountain Wild gastrodia elata BI): Alias Chijian, wind grass, dragon grass. Of orchid plants. Gastrodia tuber medicine. Interest-bearing wind analgesic effect. Located in the Ministry of Thunder Thunder Shandong Ping hillside above an altitude of 1750 meters. Every July and August there is a lot of production from Guizhou Province Leishan Leigongshan listed Tianma wild primeval forest, fresh Tianma prices ranging from 30-80 yuan, is a rare quality medicines. Second, the plant characteristics Perennial herb, height 100 cm to 130 cm. Mast fleshy tubers, oblong. Grass stems erect, cylindrical, yellow red. Rootless. Degenerated into scaly leaf sheath amplexicaul. Racemes, yellow-green flowers, pot-shaped corolla irregular was crooked. Capsule oblong. Small seeds, powder. Third, the growth habit Wild Gastrodia more growth in deforested large number of residual weed and tree stumps and roots of the place or places of bamboo. Tianma that does not absorb nutrients in the root, nor green leaves make food, must be a fungus Armillaria establish a symbiotic relationship. To grow, so there is growing Tianma place, certainly a lot of Armillaria associated. Gastrodia planting should first develop a good Armillaria on the stick, wood or fungus known that the bacteria stick. Dense ring cell invasion Available stick nutrition, then Tianma bacteria cultivated in the next village, the lessons from the mycelium into Gastrodia tuber rot fungus material nourishment for Tianma growth and development. Armillaria is a facultative parasite that can live in the living roots can also saprophytic on dead tree deadwood. Armillaria is a saprophytic fungus mycelium white, countless bacteria into rhizomorph mesh knot together, showing fibrous-like, brown, white top growing point. Tianma and Armillaria temperature and humidity have certain requirements. Armillaria at 6 ℃ ~ 8 ℃ at the beginning of growth, but Tianma at 10 ℃ ~ 15 ℃ began to germinate the fastest growth both in 20 ℃ ~ 25 ℃ when more than 30 ℃ to stop growing. Armillaria and Tianma growth requires a certain humidity, soil moisture content is too low, Armillaria poor growth, Tianma also grow well; excessive moisture, inadequate soil air, not only affects the Armillaria and Tianma growth, and even cause Tianma rot. Fourth, cultivation techniques Tianma shape, size, and divided according to the different stages of growth as arrows linen, white linen, hemp and rice, hemp mother of four. White linen and hemp meters which is asexual propagation material. Chunzai and winter can be planted, Chunzai March to April, winter planted in November, a time when Tianma dormant stage, suitable for cultivation. (A) cultivation methods are: ① bacteria material plus new material law: digging a foot deep, planted layers, the lower two sides put bacteria material. Intermediate interval bacteria material put new material, bacteria village interval 1.5 cm to 3 cm. Between the two kinds of material put 3-4 hemp, hemp seed material to be placed parallel and close to bacteria, do not rely on new material, a layer of finished planting, fill the void with soil, then cover 3 cm to 6 cm thick with a thin layer of soil. Put on a layer. _ The same way as the lower, and finally 10 cm -15 cm deep mulch. ② fungus bed cultivation method: June to July nurture good bacteria bed, by digging deep 33 cm, put two, two full release of new material sandwiched between the release of new material every two bacteria sticks 2-3 segments. two timber 1.5 cm to 3 cm apart, fill the gap mulch, Serve bacteria bed. Winter or spring of the year to the second year of planting Tianma, when planted timber off the top layer of bacteria, the bacteria material between the lower soil clawed some Zairu hemp seed. After changing soil to mask the timber segment, and then planted the second layer, mulch 3 inches to 5 inches thick. (B) seed multiplication: Tianma seeds small, very large quantity, a 2-4 ten thousand fruit seeds, one can harvest the fruits of 30 or so. Propagate by seed only to solve the lack of hemp seed, vegetative propagation is an important way to long-term degradation and promote the rapid development of Tianma resolved. (C) field management: After planting Gastrodia not require special management attention to keep the soil moisture, but be careful not to water too much, so as to avoid Tianma rot. In order to maintain soil moisture may erection Jianyi Peng shade. 4-5 a year ago Tianma unearthed, hoe once. Tianma can grow in the ground for many years, with the growth of age, about two years can be considered a new strain of supplementary material. (D) Pest and Disease Control: ① harmful bacteria on Tianma, such as bacteria grow faster, they suppress Armillaria; If Armillaria vigorous growth of bacteria will be inhibited. In addition, it is necessary to prevent harm Armillaria Tianma, because both symbiotic life, such as the condition is only suitable and not suitable for the growth of Armillaria Tianma growth when Armillaria will multiply, harm Tianma. ② mole crickets, grubs, see Astragalus Pest and Disease Control section. (E) harvest processing: Winter planted the second or third year in the winter spring collection. Chunzai a year or second year of winter spring collection. Arrow hemp human medicine, white linen, hemp meters for species. When processing will take advantage of fresh Tianma Wash size of three or four levels, after the water is put into the water Tianma, the big cook 10 to 15 minutes, while the small and cook for 3-5 minutes, can be cooked in the heart prevail. After drying or dried fish simmered. (Vi) the biological characteristics: Tianma is a special kind of orchid plants, no roots, no leaves, can not absorb salts, water and nutrients directly from the soil, not the business of organic photosynthesis. The whole growth period, unless the sexual stage of about 70 days on the surface, the perennial tuber latent living in the soil, by Armillaria supply nourishment, growth and development. Special plant morphology, resulting in the growth of environmental conditions, such as special requirements, with a special living habits. Five, Tianma growth and environment 1, the terrain: Tianma in the southwest area of distribution in the range of 700-2800m above sea level; concentrated between 1400-1700m above sea level, in the high mountain forest and wild land in the bamboo forest. Generally between 800-1800m above sea level introduction and cultivation, but the altitude of 1100-1600m in the region is more appropriate. Such as soil temperature and humidity control, low-lying areas may also be introduced cultivation. Regions such as Hunan and altitude of 50m above sea level 154m in Beijing's suburbs have been successful introduction and cultivation. 2, Climate: Hi cool climate, humid environment. In summer, the temperature does not exceed 25 ℃ cooler conditions and annual rainfall 1000-1600mm, air relative humidity of 80% -90%, about 40% of the wet soil moisture conditions, Tianma grow well. Soil moisture is too large, perishable tubers, soil moisture is too small, the growth of Armillaria restricted, affecting Tianma growth. Tianma roots and leaves degradation, photosynthesis can not camp, so Gastrodia tuber growth does not require light, light only acts as the supply of heat, but the flowering as a result, have a role in seed maturation. 3, the soil: Hi grow in loose soil, humus contains more required, good permeability, good soil structure and drainage performance. Clay (eg dead Wong), and poor growth. Generally grown in acidic soil, its pH value of pH 5-6. Six, Tianma growth of Armillaria Tianma rootless leaves, lose self-support capabilities, its nutrients needed for growth by symbiosis with Armillaria by Armillaria supply nutrients. Armillaria is a kind of saprophytic mainly facultative parasitic fungi, and bacteria Soli mycelium with a variety of organic substances, and its main source of nutrition by the decomposition of wood cellulose, hemicellulose, lignin, and so on. Therefore, the key is to develop artificial cultivation of Gastrodia good bacteria and fungus Armillaria timber. Armillaria Armillaria mellea (Vahl.ex Fr.) Quel. Division white mushroom is a fungus Armillaria spp. In the alpine woods, early rotten stumps, on the roots, trunk and branches fell on often found growing wild Armillaria; especially in humid places on both sides of the creek at most. Where the growth of wild Gastrodia place has wild Armillaria. Armillaria hi slightly acidic soil. Armillaria is an aerobic facultative parasitic fungi, its growth and development, the need for adequate air. To do this in the material culture of bacteria and fungus cultures, to have appropriate ventilation conditions. When planting Tianma, soil should be well drained and loose breathable. Armillaria temperature 6 ℃ -30 ℃ could grow to 18 ℃ -25 ℃ is the optimum, exceed 30 ℃, then stop growing. Lethal temperature of 70 ℃ (5 minutes). Suitable air relative humidity of 90% soil moisture content as a separate culture of Armillaria should be 70% -80%, such as planting Gastrodia mix to 40% -50% is appropriate. Seven, Tianma growth characteristics Tianma growth period required 2-4 years. Tianma growth period, about 90% of the time in the underground growth, unearthed from hemp shoots arrows to fruit ripening, just 45-65 days. Gastrodia tuber due to the different developmental stages, there are two types of Gastrodia tuber in neonatal anesthesia. Arrow Ma Gastrodia tuber is mature, relatively large, the top has a prominent red-brown buds remarkable mouth, like "parrot mouth", to bolting fruition. Stem like an arrow, so called "Arrow Ma." Accumulation of material in its highest tuber stage, processed into finished goods is high, is the main source of goods Tianma. White linen tubers smaller than the Arrow hemp buds mouth shorter, not bolting; summer buds grow out from the thick white bud, so called "white linen", individual small white linen called "rice Ma", usually rice Aso Long developed into a year long white linen; white linen re-growth a year into arrows hemp. White linen and hemp rice breeding ability, can give birth to more children of hemp. White linen and hemp is cultivated rice species best hemp. Tianma life to go through the original sphere, rice linen, white linen, hemp arrows, Wo Ma five stages. The first three stages of vegetative growth can be called after the two phases can be called reproductive growth stages. Arrow hemp mixed with buds, winter after flowering next summer after bolting to form Wo Ma (excavated earth after bolting plants). Tianma Wo Ma is the most important in life, a brief period of earthly life. Tianma seed is very small, the naked eye in powder form, it is difficult to distinguish. The number of seeds per seed, generally 2-3 ten thousand. Seeds without endosperm, only one ovoid embryos germinate without their own source of nutrition, the need to rely on the external environment. Germination of seed germination require inoculation bacteria (purple Kei Mycena Mycena osmundicola Large) only after germination, seed germination after the original bulb formation after inoculation Armillaria need to continue growth and development. Experimental study of modern proof, Tianma sterile seeds germinate, the required nutrients are provided by the seed itself into the storage material decomposition and the surrounding solution. Eight, Tianma morphology Saprophytic perennial herb, 60-100cm, underground tubers occur, thick, fleshy, oblong or oval, about 10cm, there is no obvious link. Stems single, erect, cone-shaped, yellow red, slightly fleshy. Leaves membranous scales degradation, alternate, base clasping sheath was. Racemes, corolla irregular, mouth tilt, base dilated, was crooked pot shape. Capsule oblong to obovate; seeds and thin majority. Flowering from June to July; fruit from July to August. Nine, modern research and development Tianma contained in the "Shen Nong's Herbal Classic", the traditional rule of wind medicine for our famous authentic ingredients. Modern research shows that Gastrodia elata contain glycosides, Tianma aglycone, p-hydroxybenzaldehyde, succinic acid, β-sitosterol, sugars and other chemical components, has analgesic, anticonvulsant effect on brain disease caused by influenza virus has good effect; lower blood pressure, heart rate, increased cardiac output, the treatment of cardiovascular disease. Tianma Armillaria tablets in the treatment of neurasthenia, hypertension, coronary heart disease due to dizziness, headache, angina embolism, the effective rate of 80%. Tianma can eyesight, enhance memory, the human nervous system protection and regulation, can enhance the resolving power of the optic nerve. IAF personnel has been designed as a health food supplies and the elderly. Tianma great development potential, is the depth of research and development. Ten, Tianma pharmacological use (A) Sedation Tianma 1-5mg/kg, Tianma glycosides 50mg/kg, Tianma Eryuan 100mg/kg, vanilla alcohol, vanilla intraperitoneal injection of 200mg/kg factors could significantly inhibit the spontaneous activity. Tianma glycosides on monkeys, pigeons have a calming effect, monkey intravenous or intramuscular injection, 20 minutes appears quiet, no stress like for 2 hours. Tianma can antagonize caffeine-induced excitability and prolonging sodium pentobarbital sleep time. Tianma injection of sodium pentobarbital 5-10g/kg with chloral hydrate and sodium thiopental have a synergistic effect. This result also with different reports; Tianma Injection, go Tianma glycosides part to reduce locomotor activity of mice and synergistic effects of pentobarbital sodium, but the effect is not obvious gastrodin that gastrodin not Gastrodia active ingredient. Tianma sedation may be related to reduced excitability of the central nervous system related. (B) the impact on the drug sodium pentobarbital sleep time 1, the impact of alcohol on Vanilla cyclohexene two sodium pentobarbital sleep time vanilla alcohol prolong the rat small sleep time is about four times the control group, Hong Ying Lan Su prolonged sleep time is about 2 times. 2, the impact of Armillaria Tianma agent and pentobarbital sodium broth night's sleep time in the control group only to pentobarbital sodium, according to righting reflex as a sleep indicator. The results have significant differences with the control group administered. 3, Tianma Injection to influence Gastrodia elata glycosides and saponins part of sodium pentobarbital sleep time Gastrodia elata injection and go to sleep two part 20g/kg group than the control group, respectively, to extend the 73% and 27%, a significant difference, p <0.05, while the two groups was not affected Tianma. (C) The anticonvulsant effect Tianma can reduce animal pentylenetetrazol-induced shock and mortality according to shorten time-clonic anticonvulsant effect of artificially propagated Tianma stronger than the wild who, many times better than a single drug prolonged drug effect, mice were injected intraperitoneally Tianma agent 5g/kg etc. could prolong pentylenetetrazol clonic convulsions of incubation. Significantly improved subthreshold half of the amount of pentylenetetrazol (CDs0.), But rather the role of seizures who were not significant. Description of the role they may not be part of the spinal cord of the central nervous system. Tianma Injection 10-20g/kg intraperitoneal injection can significantly improve pentylenetetrazol of CD50, the dose can be increased to 30g/kg mice have seizures antagonism. Experimental crazy epileptic rats daily subcutaneous veins Tianma 50% ethanol extract ,0.25-g / kg ,3-6 日 crazy to stop epileptic seizures, stopping on the 10th effect disappeared. Daily injections of Hong Ying Lan alcohol 0.1-0.2g/kg, 5 date on which effective withdrawal; 1-7 effect disappeared. Tianma decoction 1/kg rabbits intravenously or 40mg/kg Hong Ying Lan alcohol may increase the electro-convulsive threshold, effectively halt epileptic seizures, control EEG epileptiform discharges. Hong Ying Lan alcohol than Tianma decoction significant role, but are not, and phenytoin. With amputations caused by mechanical stimulation pulse synthesis method experimental epilepsy rats and found that the clock rat brain seizures, brainstem norepinephrine and dopamine levels in the caudate nucleus decreased after treatment to make these parts of norepinephrine and dopamine levels rise. Tip Tianma the pulse rat experimental epilepsy treatment and adjustment mechanisms in different parts of central catecholamine metabolism. (Iv) anti-inflammatory effects Pakistan mouse ear inflammation model results indicate that soybean oil, Gastrodia elata II injection and to a certain part of the anti-inflammatory effect. (E) the impact on immune function ① Zhu stems reports, Gastrodia elata with enhanced non-specific immunity and cellular immunity. Referring to Kim Yun Fang and cane polysaccharide immune activity measurement method, taking the team C57BL mice of either sex, each batch of the same sex ,14-20g, daily ip Gastrodia elata 125mg/kg, total 7d, comparison with saline, after administration 24h, sacrificed, spleen and thymus were weighed. The results significantly increased thymus weight, with statistical significance. The experiments also showed an increased Gastrodia elata mouse thymus weight, improve mouse peritoneal macrophage phagocytosis, enhanced mouse graft-versus-host reaction. ② Zhu Liling other reports, Gastrodia elata on tissue culture of vesicular stomatitis virus (VSv) has a direct inhibitory effect. He took 20-22gC: H / Je purebred mice in the experimental group with Gastrodia elata suspension 12.5mg / only ig, day 1, every 0.4ml / only. Comparison with distilled water, continuous 7d, then each ipl280Hau/ml Newcastle disease virus (MV) 0.5ml, 6h after taking blood samples, measured by CPE method interferon titer and standard interferon correction. The results have a very significant role in the experimental group. With the same species of mice, ipl2.5mg/ml sugar concentration Tianma multi 0.2ml / only control with saline, and then were 6,12,18,24 h blood serum was separated, and the normal serum control, results in 18h and 24h produce interferon drop becomes the highest (p <o.01). (Vi) the analgesic effect With shock tail method proved cultivated and wild Gastrodia elata 5g/kg are very significant analgesic effect, wild who is strong, but they were less than 10mg/kg analgesic effect of morphine. 90 minutes after the pain of wild Gastrodia administration was 41.4%, while only artificially propagated Tianma or morphine (21.4% ~ 39.1%), subcutaneous Tianma preparations 5g/kg 2 button mouse can significantly against the body reaction caused by intraperitoneal injection of acetic acid. Hot plate method also proved to improve pain threshold effect. But it has been reported that alcohol or whether Hong Ying Ying Lan Lan Su 300mg/kg, Gastrodia elata extract injection 10-20g/kg and mouse 2-5g/kg does not improve pain threshold River, these conflicting results may be related pharmaceutical preparations related to the different experimental conditions or should be further studied. (Vii) the effect on the cardiovascular system ① on the heart Tianma liquid guinea pig heart in addition to the reign of mild heart rate, but does not affect the heart contraction. Different routes of administration may slow down the heart rate in anesthetized rats, intravenous obvious. Little change in the general QRS complex, PR interval, QT interval is often prolonged, T wave becomes high and obtuse. Gastrodia elata two glycosides and saponins Eryuan also slightly slowed heart rate, after 2 hours to return to normal. Normal home free ECG T-wave, ST segment without change, showing sinus rhythm. Elata on acute myocardial ischemia induced by pituitrin wide have a protective effect, make flattened or inverted T waves, ST segment and decreased heart rate does not significantly change agent. Gastrodin make synthetic outer cultured neonatal rat cardiomyocytes beat frequency accelerating contraction strengthened rhythm rule, no significant difference between the different dose groups; had no effect on myocardial cell morphology, but intracellular glycogen, RNA, DNA , discoloration hydrogen succinate dehydrogenase • one and a significant increase in lactate. It is considered likely to promote the synthesis of gastrodin myocardial energy metabolism, gain energy, especially in the absence of oxygen effect. Synthetic gastrodin also toxic injury of myocardial cells have a protective effect. Application of MMC cytotoxicity pathological model of myocardial injury, ran from the level observed in the synthesis of fine gastrodin MMC-induced myocardial cell degeneration can alleviate, reduce necrosis, SDll, LDII activity was significantly enhanced. This may gastrodin promote myocardial cell energy metabolism, enhance the anti-injury are closely related. ② blood vessels do not need to use as guinea pig heart Langenciorff France retired tank flow, Tianma solution (1:2000) can reduce coronary blood flow after the first increase up to 181%. Isotope "riveting measured myocardial nutritional blood flow in mice showed that intravenous injection of Tianma 10 a 20g/kg can significantly increase the" rubidium intake. These results suggest that myocardial nutritional Tianma can increase blood flow, improve cardiac circulation, increased myocardial oxygen supply, has a protective effect on myocardial ischemia. Tianma anesthetized dogs intravenous injection 1-2g/kg or Armillaria mycelium 1g/kg,, can significantly reduce coronary vascular resistance, increase blood flow. Mycelium also reduce cerebral vascular resistance increased cerebral blood flow. When Tianma or mycelium humoral agents shot directly into the coronary or carotid arteries, the role is more significant. Tianma peritoneal fluid, vein or carotid artery injection may be varying degrees of mice and rabbits increased cerebral blood flow and reduce cerebral vascular resistance. Acetyl Gastrodin 200mg/kg duodenal administration ,10-60 minutes after the blood flow in anesthetized dogs pushed significantly increased. A significant increase in blood flow in the carotid free. While no significant changes in cardiac output. Tip ether gastrodin on cerebral circulation has some _select_ive effect. Isolated rabbit ear irrigation fluid found 20-40% Tianma ll 5 minutes after injection, flow was significantly increased, up to 2.7-fold increase. Tianma was still capable of fighting vasoconstriction induced by epinephrine, diphenhydramine once dilation of blood vessels without affecting benzene, may partially against atropine. Acetyl gastrodin on vascular smooth muscle spasm. After the break outside the basilar artery of cattle into the device containing Kreb's solution, first given agonist 5-HT, the artery of the produce rapid and sustained contraction, when adding acetyl gastrodin to this 5-HT-induced antispasmodic action by the confrontation, and the performance of a significant dose-effect relationship. Compared with papaverine, strength acetyl gastrodin antagonism of 5-HT-induced spasm role is only one sixth of the former. Meanwhile prove that when the concentration of acetylcholine gastrodin 30ug/ml, after adding potassium to cause arterial spasm contraction obviously, its strength and papaverine similar Furthermore, acetyl gastrodin norepinephrine-induced rabbit aortic strips can produce relaxation, but the effect is weak. ③ impact on blood pressure in cats with acute blood pressure experiments: .. 1 Source 2 Shape cook 5 4 3 Indications pharmacological application component analysis 6 7 8 clinical application of the rational application of Gastrodia elata Eryuan II and after use. .. mild antihypertensive effect within 1-2 hours. Tianma intravenous injection in rats and rabbits have rapid antihypertensive effect, maximum reduction of 73%, more sustained l-1.5 hours. Intraperitoneal injection or duodenal administration to rats buck last longer, up to three hours. These results provide a Tianma treatment dizziness, the theoretical basis of hypertension. (Viii) the role of hypoxia Tianma Injection on atmospheric hypoxia tolerance in mice have significantly prolonged the time of death. Tolerance to low pressure (negative pressure 300mmHg) hypoxia capacity significantly. In addition, can significantly extend the pre-injection of isoproterenol (20mg/kg) and isoproterenol plus Tianma Injection (20g/kg) _set_ in the low pressure chamber survival time of mice. This indicates an increase in tissue oxygen consumption or reduce hypoxia tolerance situation, Tianma can improve the body's tolerance to hypoxia. (9) other action Tianma cultured and wild mice were significantly elevated skin temperature effect, increase home Tianma two free situ intestinal smooth muscle tone and contraction, showing different degrees of excitement Tianma bowel action. Hong Ying Lan alcohol can promote bile secretion. Rabbits injected intraperitoneally Tianma decoction 5g/kg. Have slowed respiration. Tianma Injection can inhibit increased capillary permeability induced by acetic acid in mice, inhibition of mouse ear swelling induced by xylene increase and channel resistance, and can inhibit 5-HT, PGE2-induced rat skin capillary permeability increase in paw swelling in mice agar, carrageenan rat sex and 5-HT inhibited paw swelling. (Ten) side effects Tianma extract mice by intraperitoneal injection of LD50 for 51.4-61.4g/kg (native medicine). Tianma agent mice by intraperitoneal injection of D50, was 36 1.7g/kg. Hong Ying Lan alcohol LD50 of 891.3 31.7mg/kg. Hong Ying Lan Su intraperitoneal injection of LDj50: as l8.5mg/kg. Rats were LD50: To 1.58g/kg, rats injected subcutaneously once: to 1.8g/kg; dog slow intravenous LD50 is: 0.32g/kg. Orally or intravenously in mice Tianma two 5g/KG (Hopson drug 20kg), no poisoning and death. Rabbits injected intraperitoneally Tianma agent 12g/kg, 30 minutes after the animal unresponsive, followed by ataxia and poor feeding. 5 hours after the heart rate may be increased to more than 500 beats per minute, most animals died within 48 hours. Tianma Injection intravenous 1g/kg, animal performance Fufu not move and feeding, but the ECG and EEG showed no abnormality. Hong Ying Lan Su 1g/kg 40mg/kg intravenously or orally, animals generally in good condition, no changes in the ECG and EEG. Tianma two or Hydroxybenzaldehyde mice fed 14-15, the hematopoietic system, heart, liver, kidneys and other organs were days of adverse effects. Dogs fed Armillaria broth 12ml / day for l week, no appetite, activity, liver and kidney function any adverse reactions. B phenol Gastrodin to conceive 6-15 days intragastric administration in mice and rats 37mg / (kg.d), placenta, fetal rat body weight, gender, appearance, oral and skeletal development had no significant effect. Eleven, Tianma application history Tianma is authentic ingredients. With the development of science and technology for chemical and pharmacological Tianma deepening understanding, development of Gastrodia product also expanded. In ancient times, Tianma in health care has been widely used. "Shen Nong's Materia Medica" records, Tianma has a "master fine thing to kill ghosts, poison foul smells, Jiufu Qi Li, Zhang Yin healthy fat, light-weight by year" miraculous; "doctors do not record" records, Tianma can "eliminate pain swollen lower support full, under the Han Shan blood ";" Japan Hanako Materia Medica "records, Tianma can" help fill five workers and injured seven yang, blood, resuscitation ";" Kai Bao Materia Medica "records, Tianma can" master Zhu rheumatism, limb Spasm, pediatric epilepsy wind, gas shock, Lee lassitude, strong bones ";" Compendium of Materia Medica "records," Tianma, is the liver through the air per drug. " "Q" goes: all the wind out of dizzy, all belong to the wood. Therefore Tianma into Jueyin and rule by various diseases. By Luo Tianyi goes: eye black dizziness, virtual wind for non Tianma can not cure. Tianma is the wind grass, it is God's medicine for the wind ";" pediatric drug card straight tactic "," San Franciscans overall record, "" Universal Relief "," surgical authentic "," Lantai criterion "and other records, Tianma compatibility were related drugs to treat acute convulsions, fever, convulsion, prejudiced headache, aching pain, rheumatism, athlete's foot, premature gray hair, dizziness, numbness, hand, foot and fail, liver deficiency, headache, stroke, paralysis, tetanus embolism. Moreover , but also for health. "Ben Cao Yan Yi" records, "Tianma, with roots Satsukai other drug phase, and then reflected in its success. Plus still used. As fruit or candied or cooked food, with Tianma who then have to carry food for thought for the "Qing dynasty, the Empress Dowager Cixi suffering face the wind, Tianma compatibility with other Qufenghuoluo drugs, alcohol tune into powder, hot iron affected area.; Guangxu headache, dizziness, also commonly Tianma compatibility related drugs Jianshui shampoo in the modern, Tianma in the broader health care. "Chinese Pharmacopoeia" records, Tianma has "a Pingganxifeng, chills and shock efficacy for dizziness, numbness, convulsions in children, epilepsy, hypertension, ear vertigo "." National Herbal Compendium, "it reads, Tianma" Indications hypertension, dizziness, headache, Kouyanwaixie, numbness, convulsions in children embolism. "Some doctors attributed to the effect of Tianma" three anti-, three towns, a meeting, "that anti-epileptic, anti-convulsants, anti-rheumatic, sedative, antispasmodic, analgesic, tonic. Tianma known in folk "Yelang God grass", "Compendium of Materia Medica" called "Tianma Jiufu can vigorous Qingshenjianfei." Tianma is commonly used precious ancient Chinese medicine physicians, has been 3000 years of clinical application history. attending headache, insomnia, dizziness, numbness, epilepsy, seizures, convulsions in children, high cholesterol, high blood pressure, liver, brain due to lower planted Gastrodia active ingredient content, it is very precious wild Gastrodia two thousand years ago, as people put Tianma healing magic pill, "Shen Nong's Herbal Classic" was first recorded planting Gastrodia effect, treat nerve pain, sedative hypnotic effects. Tang Dynasty "Newly Revised Materia Medica" and the Song Su Song "Materia Medica" also has in mind planted, Ming Dynasty distinguished physician Li in the "Compendium of Materia Medica" in the ancient books were discussed about the efficacy of Gastrodia summarized: Jiufu Qi, healthy fat, increasing years, eliminate bloated, leg full of blood under the Han Shan; Indications: migraine, stroke hand, foot and fail, aching pain, line step difficult, heavy waist, woman wind weakness, skin heartless, children wind phlegm convulsions, acute and chronic irritability and so on. According to modern literature describing the medicinal properties of Gastrodia broader: to Qi, the frightened, Liver, vertigo, rheumatism, strong bones. Indications: hypertension, rheumatism, back pain, eye askew, limb spasm disorder, numbness, dizziness, headache, seizures in children and so on. In recent years, clinically proven, Tianma Injection dilation of blood vessels, increase blood vessel elasticity effect on the neurological symptoms and treatment of cardiovascular diseases dizziness and lack of basilar artery caused a significant effect. Applied to the emerging aerospace medicine, to be used as high-altitude pilots Tianma brain health products, can significantly reduce the dizziness, and enhance the ability to distinguish the optic nerve; With the continuous improvement of people's living standards, Tianma positive because it can lower blood pressure, regulate the optic nerve and other functions, So Gastrodia elata and health care will become a partner in the elderly health food, so that Tianma consumer space will grow.