vegetation : Molecular biology : Medical inspection > cholesterol
Contents
No. 1
  Also known as cholesterol. "Steroids and animals important. All organizations can be synthesized in the human body, the liver is an important organ of cholesterol synthesis. Exist in the brain, nerve tissue, subcutaneous fat, blood and bile. Cholesterol metabolic disorders, cause atherosclerosis and cholelithiasis, etc..
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dǎn gù chún
  Animal fat in a chemical present in animal tissues or body fluids, cholesterol metabolic disorders can lead to atherosclerosis or gallstone
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No. 3
  Alcohol as a white crystalline, soft. Human bile, nerve tissue, higher blood levels. Under ultraviolet light in sunlight, can become vitamin D. Important raw material of synthetic sex hormones. Cholesterol metabolic disorders can cause atherosclerosis and cholelithiasis.
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About Cholesterol
  Generally know, lipids are divided into two categories. Fat (primarily triglycerides) is the most abundant lipids in the human body is a major source of energy for the body; another called lipids, are basic components of the biofilm, accounting for 5% of body weight, in addition to including the phospholipid glycolipids, there are very important called cholesterol.
  Cholesterol, also known as cholesterol. A cyclopentane derivative of the Philippines and more hydrogen. Early in the 18th century found that people from cholesterol gallstone, a chemist in 1816 with the Marshall lipid nature of this kind of material called cholesterol. Cholesterol exists in animals, particularly brain and nerve tissue is most abundant in the kidney, spleen, skin, liver and bile levels are high. Similar to its solubility and fat, insoluble in water, soluble in ether, chloroform and other solvents. Cholesterol is essential for animal tissue cells is an important material, it is not only involved in the formation of cell membranes, and the synthesis of bile acids, vitamin d and the raw material for steroid hormones.
  High-density cholesterol is divided into two kinds of cholesterol and LDL cholesterol, the former has a protective effect on the cardiovascular, often called "good cholesterol", which is high, will increase the risk of coronary heart disease, often called " bad cholesterol. " Per unit of cholesterol in the blood at 140 ╠ 199 milligrams, is relatively normal cholesterol levels.
  Cholesterol is a body part and a long stay in the side chain composition. The total amount of cholesterol in the body accounts for 0.2% of body weight, bone contains about 10 mg, containing about 100 mg of skeletal muscle, visceral and more in the 150 to 250 milligrams, slightly higher content of liver and skin, about 300 mg. Brain and nerve tissue was the highest, per 100 grams of tissue containing about 2 grams, the total amount of the total body about l / 4.
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Application of cholesterol
  Cholesterol in the body has a wide range of physiological functions, but the overdose would lead to high cholesterol, have a negative impact on the body. Modern studies have found that atherosclerosis, venous thrombosis and gallstones and high cholesterol are closely related. If high cholesterol is a simple dietary modification is the best approach, if accompanied by high blood pressure is the best case in the monitoring of blood pressure as long as medically determined to be high blood pressure, you need to use antihypertensive drugs. Hypercholesterolemia, atherosclerosis is the result of a very important reason, so please attention.
  Nature of cholesterol mainly in the animal food among the plants without cholesterol, but there are very similar to the structure of the material and cholesterol - plant sterols. Plant sterols induced atherosclerosis without effect. In the mucosa, plant sterols (especially Valley steroids) for competitive inhibition of cholesterol absorption.
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The distribution of cholesterol
  Although the cholesterol found in animal foods being, but different animals and different parts of animals, the cholesterol content is very inconsistent. In general, the cholesterol content is higher than bushmeat poultry fat than lean meat, shellfish and molluscs than ordinary fish, and egg yolk, fish roe, animal offal is the highest cholesterol levels.
  Typically, 100 grams of food each less than 100 mg of cholesterol called low-cholesterol food foods such as eel, prostitution, carp, pig meat, bovine meat, sheep meat, duck, etc.; to 100 grams of cholesterol content in food is 100 to 200 mg of food called moderate cholesterol foods, such as grass carp, crucian carp, silver carp, eels, eel, turtle, crab, pork chops, chicken, etc.; and 100 grams of food each cholesterol from 200 to 300 mg of food, said high cholesterol foods, such as kidney, liver, tripe, shellfish meat, termite meat, egg yolk, Crab and so on. Should be minimal in patients with hypercholesterolemia to eat or not eat high-cholesterol food.
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About Cholesterol
  In the treatment of the role of cholesterol in food, there are two distinct one-sided view. One view is that cholesterol is extremely harmful to not eat. One-sided view that this is due to people who hold this view on the role of cholesterol in the body lack of clear understanding. In fact, cholesterol is a component of cell membranes, involved in a number of steroid hormones and bile acid biosynthesis. Since many other foods containing cholesterol also very rich in nutrients, eat the food if too much can easily lead to nutritional imbalance, leading to anemia and other diseases.
  Another view is that cholesterol in the human body without much damage, people can enjoy uptake. This view is false, is due to hyperlipidemia, lack of understanding of the pathogenesis of coronary heart disease. Long-term excessive intake of food cholesterol will lead to atherosclerosis and coronary heart disease incidence and development.
  How much to eat in a day more appropriate to the issue of cholesterol, is generally believed that healthy adults and is not associated with coronary heart disease or other atherosclerotic disease in patients with hypercholesterolemia, a daily intake of cholesterol should be below 300 mg in associated with coronary heart disease or other atherosclerotic disease in patients with hypercholesterolemia, a daily intake of cholesterol should be below 200 mg.
  The best in the diet containing dietary fiber-rich foods, such as: celery, corn, oats, etc.; tea tea pigment can reduce total blood cholesterol, prevent atherosclerosis and thrombosis, green tea better than black tea; vitamin c and e can reduce blood fat, adjust the lipid metabolism, they are dark or green plants (vegetables, fruits) and high content of beans. Limit high-fat foods: such as organ meats, fresh vegetable oil do not eat animal oil.
  Blood alcohol may increase high-density lipoprotein, strengthening the role of prevention and treatment of hypercholesterolemia. Daily intake of alcohol consumption to no more than 20 grams of alcohol (wine not exceeding 50 grams) is appropriate, the wine more appropriate, but must strictly limit the intake.
  Cholesterol and more foods are: egg yolk, animal brain, liver and kidney animals, cuttlefish (squid), crab roe, crab ointment. Crab with crab meat per 100 grams of high cholesterol containing 235 milligrams of cholesterol per 100 grams of 460 mg of cholesterol in the Crab. Higher levels of cholesterol in liver, according to analysis in each 100 grams of liver, containing approximately 368 milligrams of cholesterol.
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Eat the reasonable control of cholesterol
  Low-density lipoprotein cholesterol (referred to ldl-c), can cause damage to the artery; and high-density lipoprotein cholesterol (referred to hdl-c), is a function of the arteries clean and clear. Here are some experts recommend the diet to reduce body ldl-c levels, and increase the hdl-c content.
  1, more fish
  Ω-3 fatty acids for one (found in tuna, mackerel, salmon and sardines and other fish) on the hdl-c of the impact of the research shows that when the number of fish per week or even daily 1 1 , can effectively reduce the intake of saturated fat.
  2, eat more foods rich in fiber
  Bread, whole grain and high fiber content of foods, can reduce the body ldl-c levels. Nutrition experts point out that in order to achieve the effect of cholesterol, dietary fiber to reach 15 to 30 grams.
  Canada in the breakfast plate of blackberries, add half a bowl of lentils for lunch, dinner by adding a whole-wheat pasta, plus five pairs of semi-dry cut open the peach as a snack.
  3, eat soy products
  Vegetable protein such as tofu and soy products expanded, the plant contains a natural chemical substances called isoflavones. Research shows that this chemical will help to damage arteries ldl-c purged from the body.
  4, adequate intake of vitamin c
  Tufts University in Massachu_set_ts, conducted the study showed that blood levels of vitamin c body hdl-c and proportional to the content. Experts suggest eating 3 to 4 copies per day of vitamin c rich foods, such as citrus fruits, potatoes, broccoli, cauliflower, strawberries, papaya and dark green leafy vegetables, can increase blood levels of vitamin c to improve the number of body hdl-c, to ensure patency.
  health world tips:
  Cholesterol is an essential human nutrient. It is not only the structural component of the body, or the synthesis of many important raw materials. Not eat food containing too much cholesterol, could easily lead to anemia, reduce the body's resistance; but long-term high intake of cholesterol, is not conducive to good health, will increase serum cholesterol levels, increase the risk of cardiovascular disease risk. Therefore, the scientific method to promote adequate intake of dietary cholesterol.
  Cholesterol and low cholesterol foods are: all plant foods, eggs, egg whites, poultry, dairy, fish, etc.;
  Cholesterol and more foods are: egg yolk, animal brain, liver and kidney animals, cuttlefish (squid), crab roe, crab ointment.
  Generally believed that cholesterol intake to less than 300 mg per day is appropriate (the equivalent of one egg yolk with a cholesterol).
  health world tips:
  The researchers also found that non-smoking, proper drink some wine and a few times a week exercise to improve heart function is to improve the human body hdl-c number 3 key.
  l eat less high fatty foods
  Animal liver, eggs, red meat such as beef and mutton, are higher levels of ldl-c food, eat these foods, do not help reduce the amount of cholesterol in the body.
  Nancy? Ernst Maryland National Heart, Lung, and Blood Institute staff, she pointed out that in any way to lower cholesterol in the diet, saturated fats should be as far as possible to get from the heat, reduce to a day diet 10% of total calories. Because of excessive saturated fat will increase the body burden of the system responsible for removal of cholesterol, leading to artery blockage.
  l the proportion of fat intake redistribution
  Daily intake of fat the body is broadly divided into saturated fat (mostly found in meat and other foods), a variety of non-saturated fats (mostly found in vegetable oils) and a single non-saturated fat (found in canola oil and olive oil .)
  Experts suggest changes to the daily dietary intake of these three kinds of fat percentage, can reduce the body ldl-c levels. For people with higher cholesterol levels, the optimal distribution of 3 fat ratio 7:10: 13. In other words, from the saturated fat intake of calories, total intake should be reduced to 7% or less; from a variety of non-saturated fat intake of calories, total intake should be reduced to below 10%; from single non-saturated fat intake of calories, total intake can be increased to 13% or more.
  health world tips: doctors advise
  l The patients diagnosed with high cholesterol should be regular monitoring by a doctor and treatment guidance.
  l vitamin e supplements, while not taking anticoagulant drugs.
  The daily consumption of vitamin e l is 30iu (international units of vitamin). However, when doctors recommend taking vitamin e supplements to help lower cholesterol, doctors often can achieve the recommended daily amount of at least 100iu. Although expert opinion is that the use of vitamin e 600iu dose within the range are all safe and sound; But experts also stressed that taking a specific quantity, method, time and attention, to be like with doctors.
  In addition, two hundred thousand, according to our clinical data confirm that tea extracts - "tea pigments" to have significant effect to regulate cholesterol, non-toxic side effects, doctors can determine whether to take after diagnosis [tea pigment capsule].
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About Cholesterol
  Generally know, lipids are divided into two categories. Fat (primarily triglycerides) is the most abundant lipids in the human body is a major source of energy for the body; another called lipids, are basic components of the biofilm, accounting for 5% of body weight, in addition to including the phospholipid glycolipids, there are very important called cholesterol.
  Cholesterol, also known as cholesterol. A cyclopentane derivative of the Philippines and more hydrogen. Early in the 18th century found that people from cholesterol gallstone, a chemist in 1816 with the Marshall lipid nature of this kind of material called cholesterol. Cholesterol exists in animals, particularly brain and nerve tissue is most abundant in the kidney, spleen, skin, liver and bile levels are high. Similar to its solubility and fat, insoluble in water, soluble in ether, chloroform and other solvents. Cholesterol is essential for animal tissue cells is an important material, it is not only involved in the formation of cell membranes, and the synthesis of bile acids, vitamin d and the raw material for steroid hormones.
  High-density cholesterol is divided into two kinds of cholesterol and LDL cholesterol, the former has a protective effect on the cardiovascular, often called "good cholesterol", which is high, will increase the risk of coronary heart disease, often called " bad cholesterol. " Per unit of cholesterol in the blood at 140 ╠ 199 milligrams, is relatively normal cholesterol levels.
  Cholesterol is a body part and a long stay in the side chain composition. The total amount of cholesterol in the body accounts for 0.2% of body weight, bone contains about 10 mg, containing about 100 mg of skeletal muscle, visceral and more in the 150 to 250 milligrams, slightly higher content of liver and skin, about 300 mg. Brain and nerve tissue was the highest, per 100 grams of tissue containing about 2 grams, and its total body volume of about l / 4.
  There are a large number of eukaryotic cell membrane _insert_ion of cholesterol between the membrane phospholipids, can enhance the stability of membrane lipid bilayer, increasing lipid order and reduce its fluidity, regulating membrane mechanical properties.
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Function of cholesterol
  (1) the formation of bile acid: Bile produced in the liver and stored in the gallbladder, after release into the small intestine to digest fat and being mixed. The function of bile is to large particles of fat into small particles, making it easy and small intestine enzyme. Tail in the small intestine, 85% to 95% of the bile is re-absorbed into the bloodstream, the liver re-absorption of bile acids so as to continuously cycle, the remaining bile (5% -15%) excreted with the feces. Liver bile acid to be produced to make up for this new 5% to 15% loss, then you need cholesterol.
  (2) constitute the cell membrane: cholesterol constitutes an important component of cell membranes, the membrane surrounding each cell in the body, the cholesterol to its basic components, accounting for more than 20% of the plasma membrane lipids. It has been discovered that the lack of cholesterol fed animals, the results of the red blood cell fragility of these animals, likely to cause cell rupture. The results show that the temperature is high, cholesterol can prevent the disorder in bilayer; the temperature is low but also interfere with the orderly and prevent the formation of liquid crystal to maintain its liquidity. So, imagine if there is no cholesterol, cells can not maintain normal physiological function, life will be terminated.
  (3) Synthetic hormones: hormones is to coordinate the multi-cellular organism metabolism in different cell chemical messenger involved in the metabolism of the body of various substances, including sugar, protein, fat, water, electrolytes and minerals, metabolism, the maintenance of the human body normal physiological function is very important. Human adrenal cortex and gonads by the release of various hormones such as cortisol, aldosterone, testosterone, estradiol and vitamin D are all steroid hormones, its precursor is cholesterol. `
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Eat the reasonable control of cholesterol
  Low-density lipoprotein cholesterol (the LDL-C), can cause damage to the artery; and high-density lipoprotein cholesterol (the HDL-C), then with clean clear arterial function. Here are some experts recommend the diet to reduce LDL-C levels in humans, and increased HDL-C content.
  1, more fish
  Ω-3 fatty acids for one (found in tuna, mackerel, salmon and sardines and other fish) on the hdl-c of the impact of the research shows that when the number of fish per week or even daily 1 1 , can effectively reduce the intake of saturated fat.
  2, eat more foods rich in fiber
  Bread, whole grain and high fiber content of foods, can reduce the body ldl-c levels. Nutrition experts point out that in order to achieve the effect of cholesterol, dietary fiber to reach 15 to 30 grams.
  Canada in the breakfast plate of blackberries, add half a bowl of lentils for lunch, dinner by adding a whole-wheat pasta, plus five pairs of semi-dry cut open the peach as a snack.
  3, eat soy products
  Vegetable protein such as tofu and soy products expanded, the plant contains a natural chemical substances called isoflavones. Research shows that this chemical will help to damage arteries ldl-c purged from the body.
  4, adequate intake of vitamin C
  Tufts University in Massachu_set_ts, conducted the study showed that blood levels of vitamin C the body hdl-c and proportional to the content. Experts suggest eating 3 to 4 copies per day of vitamin C rich foods, such as citrus fruits, potatoes, broccoli, cauliflower, strawberries, papaya and dark green leafy vegetables, can increase blood levels of vitamin C to improve the number of body hdl-c, to ensure patency.
  Health world tips:
  Cholesterol is an essential human nutrient. It is not only the structural component of the body, or the synthesis of many important raw materials. Not eat food containing too much cholesterol, could easily lead to anemia, reduce the body's resistance; but long-term high intake of cholesterol, is not conducive to good health, will increase serum cholesterol levels, increase the risk of cardiovascular disease risk. Therefore, the scientific method to promote adequate intake of dietary cholesterol.
  Cholesterol and low cholesterol foods are: all plant foods, eggs, egg whites, poultry, dairy, fish, etc.;
  Cholesterol and more foods are: egg yolk, animal brain, liver and kidney animals, cuttlefish (squid), crab roe, crab ointment.
  Generally believed that cholesterol intake to less than 300 mg per day is appropriate (the equivalent of one egg yolk with a cholesterol).
  Health world tips:
  The researchers also found that non-smoking, proper drink some wine and a few times a week exercise to improve heart function is to improve the human body hdl-c number 3 key.
  l eat less high fatty foods
  Animal liver, eggs, red meat such as beef and mutton, are higher levels of ldl-c food, eat these foods, do not help reduce the amount of cholesterol in the body.
  Nancy? Ernst Maryland National Heart, Lung, and Blood Institute staff, she pointed out that in any way to lower cholesterol in the diet, saturated fats should be as far as possible to get from the heat, reduce to a day diet 10% of total calories. Because of excessive saturated fat will increase the body burden of the system responsible for removal of cholesterol, leading to artery blockage.
  l the proportion of fat intake redistribution
  Daily intake of fat the body is broadly divided into saturated fat (mostly found in meat and other foods), a variety of non-saturated fats (mostly found in vegetable oils) and a single non-saturated fat (found in canola oil and olive oil .)
  Experts suggest changes to the daily dietary intake of these three kinds of fat percentage, can reduce the body ldl-c levels. For people with higher cholesterol levels, the optimal distribution of 3 fat ratio 7:10: 13. In other words, from the saturated fat intake of calories, total intake should be reduced to 7% or less; from a variety of non-saturated fat intake of calories, total intake should be reduced to below 10%; from single non-saturated fat intake of calories, total intake can be increased to 13% or more.
  Health world tips: doctors advise
  l The patients diagnosed with high cholesterol should be regular monitoring by a doctor and treatment guidance.
  l take vitamin E supplements at the same time, not taking anticoagulant drugs.
  The daily consumption of vitamin E l is 30IU (international units of vitamin). However, when doctors recommend vitamin E supplements to help lower cholesterol, doctors often can achieve the recommended daily amount of at least 100IU. Although expert opinion is that the use of Vitamin E 600IU dose within the range are all safe and sound; But experts also stressed that taking a specific quantity, method, time and attention, to be like with doctors.
  In addition, two hundred thousand, according to our clinical data confirm that tea extracts - "tea pigments" to have significant effect to regulate cholesterol, non-toxic side effects, doctors can determine whether to take after diagnosis [tea pigment capsule].
  In general, there are two reasons for the low cholesterol. First secondary low-cholesterol, common in hyperthyroidism, liver damage such as hepatitis, cirrhosis of the liver and so on. Another is the primary low-cholesterol, and more from the diet is not balanced, long-term vegetarian, the partial eclipse, caused by low intake of cholesterol.
  After excluding the possibility of other diseases, to maintain normal blood cholesterol levels, we must develop a balanced diet. Cholesterol low, you can eat more fish, animal offal, eggs and other food.
  What to eat to lower cholesterol
  1. Eat or not eat animal organs, egg yolk and other high cholesterol foods, intake of cholesterol in the diet (less than 300 mg a day). Cholesterol in the blood mainly (70%) synthesized in the liver, only a small part (30%) from food, to reduce cholesterol intake alone does not fundamentally treat high cholesterol, but the control of food intake on cholesterol lower cholesterol is still helpful. According to the standard American Heart Association recommended daily intake of cholesterol should be less than 300 mg or less, and 1 egg yolk cholesterol of 250 to 290 mg; 2 two halogen cook as much as a good liver cholesterol 469 mg.
  2. Low fat meat, and Hun, reduce saturated fat intake. Wide range of saturated fat found in meat, eggs, dairy foods, especially fat, saturated fat and visceral Hun content of most. Saturated fat can promote blood low-density lipoprotein cholesterol (LDL-C) students with high role, its effectiveness even more than cholesterol itself.
  4. Olive oil, tea oil, corn oil and rapeseed oil contain monounsaturated fatty acids can reduce low-density lipoprotein cholesterol (LDL-C) role. In the daily diet with soybean oil, peanut oil and other vegetable oils with food.
  5. Fish oil and lecithin can reduce the role of lipids, but its role is mainly for increased triglycerides, cholesterol-lowering effect is small (of course, still be useful.)
  6. Vitamin C, vitamin E and other ingredients with antioxidant Although not directly reduce cholesterol in the blood, but help to reduce harmful cholesterol in the blood vessels.
  】 【Cholesterol content in food
  Per 100 grams food
  2670 sheep and 3100 cattle porcine brain 1813 brain 2099 Yellow Goose
  1705 duck egg yolk yellow oval 2015 704 1522 Yellow preserved eggs
  Eggs, 680 quail eggs, preserved eggs 69 duck eggs 634 3640
  158 896 freshwater shrimp shrimp shrimp Shrimps 608 738
  96 of 150 anchovies shrimp mandarin carp 93 330
  Grass carp 83 herring 90 77 81 Turtle
  97 butterfish large yellow croaker octopus 79 68 86 salmon
  186 Barracuda 128 water, fat eel squid squid 275 265
  Mandarin fish eel 117 sub 460 sub 495 carp fish loose 240
  235 crabs jellyfish jellyfish skin leather water, fat 16 5 161 Yang Gan
  Bovine liver 429 liver 257 515 158 duck
  234 sheep and 314 cattle lung lung 215 lung 158 pig heart
  125 sheep and 130 beef heart heart pig tongue 147 116 Yangshe
  125 405 cattle tongue kidney 340 kidney 340 Yang Shen
  Yang Du 124 159 340 tripe tripe pork broth 159
  Sheep, 111 beef broth beef broth Fertilizer 194 148 173 mutton fat
  Lean pork, pork fat 77 107 63 lean beef, lamb, lean 65
  83 chicken, rabbit sausage, Guangdong 101 123 117 duck
  Beijing 72 ham sausage garlic intestine 61 69 70 Fen Chang
  Goat milk 34 milk 13 yogurt 12 39
  Whole milk powder skim milk powder 28 104 Lian Lian Yang You Cantharellus 107 110
  163 peanut butter, margarine 0 0 0 fruit
  Vegetables, potatoes 0 0
  Generally believed that cholesterol intake to less than 300 mg per day is appropriate (the equivalent of one egg yolk with a cholesterol).
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And release of cholesterol from the liver means
  Cholesterol is the body's most abundant steroid compounds, both as a cell membrane's composition, but also steroid hormones, bile acids and vitamin D precursors. So for most organizations, to ensure the supply of cholesterol to maintain its metabolic balance is very important.
  Cholesterol exists in the body tissues, of which about 1 / 4 distribution in the brain and nervous tissue, brain tissue accounted for about 2% of the total weight. Liver, kidney and intestine and other internal organs and skin, adipose tissue also contain more cholesterol per 100g tissue containing about 200 to 500mg, to the liver for up to, and less muscle, adrenal gland, ovary and other organizations can be up to 1% cholesterol -5%, but the total rare.
  Source of human steroid synthesis by the body and from food intake, normal daily diet contains about cholesterol, 300-500mg, mainly from animal organs, egg yolk, butter and meat. Plant foods contain cholesterol, and contain plant sterols such as β Valley sterol, ergosterol, etc., they are not easily absorbed by the body, excessive intake can inhibit the absorption of cholesterol.
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About Cholesterol
  Generally know, lipids are divided into two categories. Fat (primarily triglycerides) is the most abundant lipids in the human body is a major source of energy for the body; another called lipids, are basic components of the biofilm, accounting for 5% of body weight, in addition to including the phospholipid glycolipids, there are very important called cholesterol (cholesterol).
  High-density cholesterol is divided into two kinds of cholesterol and LDL cholesterol, the former has a protective effect on the cardiovascular, often called "good cholesterol", which is high, will increase the risk of coronary heart disease, often called " bad cholesterol. " Blood cholesterol levels in the 140-199 milligrams per unit, is relatively normal cholesterol levels.
  Cholesterol is a steroid and a long side chain part of the composition. The total amount of cholesterol in the body accounts for 0.2% of body weight, bone contains about 10 mg, containing about 100 mg of skeletal muscle, visceral and more in the 150 to 250 milligrams, slightly higher content of liver and skin, about 300 mg. Brain and nerve tissue was the highest, per 100 grams of tissue containing about 2 grams, and its total body volume of about l / 4.
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Abnormal cholesterol treatment and care
  High-density cholesterol levels: good, not control
  Low LDL cholesterol: a good thing, not control, we should remember that a high "high" low "low" is a good thing. Here we talk about the low-density cholesterol, low high-density lipoprotein cholesterol treatment and care.
  Typically low-density lipoprotein (LDL) oxidation state non-existence, LDL oxidation would accelerate the occurrence of atherosclerosis. Therefore prevent LDL oxidation and moderately lower LDL】 【prevention and treatment of atherosclerosis is of great significance. High-density lipoprotein】 【hyperlipidemia drug therapy, may consider using lipid regulating drugs. Many species of lipid regulating drugs, the effect is different, but its mechanism in terms of no more than interfere with lipid metabolism in one or several links, such as the reduction of lipid absorption or excretion of accelerating the decomposition of lipids, interfere with liver LDL lipoprotein synthesis or prevent the transmission from the liver into the plasma and so on.
  1. To reduce the plasma】 【low-density lipoprotein cholesterol, lipid-based drugs. Include:
  ① bile acid chelating agents: such as test to enamine (cholestyramine) and test to back Park (down Danning).
  ② HMG-CoA reductase inhibitors (statins), has been in clinical use are lovastatin, simvastatin, pravastatin, atorvastatin Buddha. Also, as Liping of, to be appropriate, such as Lipitor. Defects may lead to rhabdomyolysis, especially when combined with fibrates.
  2. To prevent】 【low-density lipoprotein cholesterol oxidation of drugs are:
  Astaxanthin, lutein, b-carotene, CoQ10, anthocyanins, fungus spores, tea polyphenols, of which the highest astaxanthin, clinical studies have confirmed that when the volunteers daily doses of 1.8,3.6, Astaxanthin 14.4 and 21.6mg for 2 weeks, LDL oxidation time was extended by 5.0%, respectively, 26.2%, 42.3% and 30.7%; which can prevent the occurrence of atherosclerosis.
  3. To enhance high-density lipoprotein drugs:
  Receiving estrogen insulin or certain drugs (such as niacin, vitamin E, heparin, etc.) treatment also increased astaxanthin can significantly enhance the human high-density lipoprotein cholesterol.
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Chinese Pharmacopoeia 2005 Edition
  Name:
  Cholesterol
  Pinyin:
  Danguchun
  English name:
  Cholesterol
  Base of the original:
  This product is from cattle, sheep, porcine brain is extracted, processed.
  Characters:
  This product is white, white crystal or crystalline powder. Gas micro.
  Identification:
  (1) to take this product 10mg, 1ml chloroform plus allows the dissolved, add sulfuric acid 1ml, chloroform layer was blood red, sulfuric acid layer was the green fluorescence.
  (2) To about 5mg, plus allows the dissolved chloroform 2ml, 1ml and research vinegar 1 drop of sulfuric acid, which was pink, red immediately after the change until bright green and blue.
  Check:
  The product melting point of not less than 140 ℃ (Annex Ⅶ C). Alcohol degree to take this product 0.4g, plus ethanol 50ml, warm to fully dissolved, and chill for 2 hours, the solution should be clarified and should not precipitate.
  Acidity accurately weighed this product 3g, _set_ conical flask, add 10ml move allows the dissolved ether, precision plus sodium hydroxide solution (0.1mol / L) 10ml, shake for 1 minute, slowly heating the ether removed, boiled 5 minutes, let cool, add 10ml of water and 2 drops of phenolphthalein solution, with the sulfuric acid solution Q (0.1mol / L) titrated to the end, and the blank test. Consumption of the test the difference between consumption and the blank test should not be too 0.5ml.
  Drying of this product, dried at 105 ℃ for 3 hours, less weight loss may not have 1.0% (Appendix Ⅸ G).
  Chi residues of this product structure 1.0g, according to inspection (Appendix Ⅸ J), not over 0.2%.
  Uses:
  Artificial bezoar for raw materials.
  Storage:
  Closed, dark.
  Chinese and Western medicine Category:
  Chinese medicine (herbs and Pieces)
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Medical Dictionary
  Also known as cholesterol. A cyclopentane derivative of the Philippines more than hydrogen, the structure shown in Fig. Early in the 18th century found that people from cholesterol gallstone, a chemist in 1816 with the Marshall lipid nature of this kind of material called cholesterol. Cholesterol exists in animals, particularly brain and nerve tissue is most abundant in the kidney, spleen, skin, liver and bile levels are high. Similar to its solubility and fat, insoluble in water, soluble in ether, chloroform and other solvents. Cholesterol is essential for animal tissue cells is an important material, it is not only involved in the formation of cell membranes, and the synthesis of bile acids, vitamin D and steroid hormones in the raw materials.
  Normal serum total cholesterol in China is about 182.5 ± 4.3 mg%. High cholesterol in the blood that cholesterol metabolism disorders may occur. Coronary atherosclerosis in patients with serum cholesterol levels are often high. Therefore, the clinical laboratory serum cholesterol levels will help to diagnose certain diseases. Insist on participating in physical exercise, try to avoid eating high cholesterol foods is an effective way to prevent coronary heart disease.
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Ministerial standards of medicine
  Pinyin: Danguchun
  English name: Cholesterol
  Page number: E6-97
  C27H46O386.67
  【Properties】 White flake crystal; no foul.
  The product in acetone, chloroform, ethyl ether, ethyl acetate, petroleum ether solution, slightly soluble in ethanol, insoluble in water.
  Melting point of the melting point of the product (China Pharmacopoeia 1995 edition two Appendix Ⅵ C) to 147 ~ 150 ℃.
  Than the rotation of this product, accurately weighed, add dissolved and made dioxane containing 20mg per 1ml of solution, measured according to the law
  _Set_ (China Pharmacopoeia 1995 edition two Appendix Ⅵ E), than the rotation should be -34 ° to -38 °.
  Identification (1) To about 10mg, 1ml dissolved in chloroform, adding sulfuric acid 1ml, chloroform layer was blood red, sulfur
  Side acid layer was green fluorescent light.
  (2) To about 5mg, 2ml chloroform allows the dissolved, add acetic anhydride 1ml, 1 drop of sulfuric acid, which was pink, rapidly becomes
  Blue, and finally was bright green.
  Check】 【solubility of this product 0.5g, plus ethanol 50ml, allows the dissolved after the warm, sit for 2 hours, not production
  Health precipitation or turbidity.
  Acidity of this product 1.0g, _set_ conical flask with stopper, add ethyl ether 10ml dissolved, precision plus 0.1mol / L hydrogen
  Sodium 10ml, shake for about 1 minute, slowly heated to remove ether, boiling for 5 minutes, let cool, add water, 10ml, the magnetic
  Stirring, add 2 drops of phenolphthalein indicator solution, titration with sulfuric acid solution (0.05mol / L) titrated to a pink disappear. At the same time make a blank
  Test. Titration of blank test solution consumed ml of sulfuric acid and sulfuric acid consumption of the test a few milliliters of titration solution should not be too bad
  0.5ml.
  Drying of this product, dried at 105 ℃ to constant weight, shall not be less than 0.3% weight loss (China Pharmacopoeia 1995
  Version two Appendix Ⅷ L).
  Residue on ignition shall not be over 0.1% (Chinese Pharmacopoeia 1995 edition two Appendix Ⅷ N).
  【Action and Uses】 emulsifiers, artificial bezoar material.
  【Storage】 sunscreen, sealed and stored.
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Encyclopedia
  danguchun
  Cholesterol
  cholesterol
  The main steroid substances the body. Is both an important component of cell membranes, but also steroid hormones. Vitamin D and bile acid precursors. The human body contains about 140g of cholesterol. People from the daily dietary intake of 0.3 ~ 0.8g can be of exogenous cholesterol, mainly from meat, liver, offal, brain, egg yolk and cream and so on. Human endogenous synthesis of cholesterol per day is also about 1g. Cholesterol in the body very uneven. Total cholesterol, body 1 / 4 exists in the brain and nervous tissue, and the remaining liver tissue were higher. 
    
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English Expression
  1. n.:  cholesterol,  cholesterin,  fatty substance found in animal fluids and tissue, thought to cause hardening of the arteries
French Expression
  1. n.  cholestérol
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